
Tvardi Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in the development of novel, oral, and small molecule therapies targeting signal transducer and activator of transcription 3 (STAT3) to treat inflammatory and proliferative diseases with significant unmet need in the United States. The company's lead product candidates include TTI-101, which is in Phase 1b/2 clinical development stage for fibrosis-driven diseases with an initial focus on idiopathic pulmonary fibrosis (IPF), and hepatocellular carcinoma (HCC); and TTI-109, an oral, small molecule STAT3 inhibitor which is in Phase-1 clinical trial stage. Tvardi Therapeutics, Inc. was founded in 2017 and is based in Sugar Land, Texas.
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Corporate PresentationAug 14, 2026
Tvardi Therapeutics, Inc. is a clinical-stage biotechnology company developing novel, oral, small molecule therapies targeting STAT3. Their lead candidate, TTI-101, is in Phase 1b/2 clinical development for fibrosis-driven diseases, including idiopathic pulmonary fibrosis and hepatocellular carcinoma. TTI-109, another oral STAT3 inhibitor, is in Phase 1 clinical trials. Founded in 2017, Tvardi aims to address significant unmet needs in inflammatory and proliferative diseases.
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